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Trimethoprim-Sulfamethoxazole and Warfarin: Why INR Rises and How to Stay Safe
Medications

Trimethoprim-Sulfamethoxazole and Warfarin: Why INR Rises and How to Stay Safe

Trimethoprim-sulfamethoxazole can cause dangerous INR spikes in people taking warfarin, increasing bleeding risk. Learn why this happens, who’s most at risk, and how to stay safe with proper monitoring and alternatives.

  • Dec, 4 2025
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